"The placenta responds to both natural chemicals as well as synthetic chemicals that the body misinterprets as natural chemicals, but the body doesn't have the ability to mitigate the detrimental effects of such industrial-made chemicals," Rosenfeld said.
Serotonin, while commonly associated with the feeling of happiness, is a natural chemical that can impact a person's functions, including their emotions and physical activities such as sleeping, eating and digesting food. Rosenfeld adds that the placenta serves as a primary source of serotonin for fetal brain development in both mice and humans. "This mouse model is the best model we have now to simulate the possible effects of BPS during human pregnancy, because the placenta has a similar structure in both mice and humans." "Synthetic chemicals like BPS can penetrate through the maternal placenta, so whatever is circulating in the mother's blood can easily be transferred to the developing child," said Rosenfeld, a professor of biomedical sciences in the College of Veterinary Medicine, investigator in the Bond Life Sciences Center, and research faculty member for the Thompson Center for Autism and Neurobehavioral Disorders at MU. She said the placenta serves as a historical record of what an unborn child faces while in the womb the placenta also can transfer whatever the mother might be exposed to in her blood, such as harmful chemicals, into the developing child. In the study, Rosenfeld and her colleagues focused on examining the effects of BPS on a mouse's placenta. As these adverse health effects have become more widely known, companies have turned to using alternative chemicals to develop plastic products - namely water bottles and food containers - and often labeling them "BPA-free." However, MU scientist Cheryl Rosenfeld warns these chemical alternatives, such as bisphenol S (BPS), still aren't safe for people to use. do you even know who she is?Īs seen on YouTube! The pilot episode of Negative Nancy, remastered! A terrible boss, a terrible waitress, a terrible crime! See where it all began… can you have the perfect day?Įach story features many branching paths: decisions you make can completely change the course of the story!Ĭollect mementos to remind you of all adventures you’ve had with Nancy.For decades, scientists have studied BPA extensively in animal models with results indicating the chemical plays a role in early pregnancy loss, placental diseases and various negative health outcomes after birth. Who’s going to stop her… you? If you think being fired is enough to escape. It’s that customer, and if she can’t speak to the manager she’s going right to the top. Road trips, wellness retreats, the sweet allure of revenge. What would you do with fifteen minutes of fame? When a famous StreamTuber comes to MegaMart, everything changes.
They say the more you remember, the more you’ve lost… but what if you have nothing to lose? Heavily armed customers, conspiracy theorists, and a MegaMart under MegaSiege! Forgetting this shift? Forget about it! You’ll be solving crimes, serving customers, making and losing friends-just like real life! Help Nancy express herself by navigating tense and delicate situations.Īll the fun of working retail with none of the pay. Play as Nancy in a short game with four unique, branching stories. if they want to take you on they'll have to get in line! Annoying StreamTubers, delusional bosses, and angry customers. You work a terrible job at Megamart with your best friend, but most of the time that’s the least of your problems. You are Nancy, a retail clerk who can only say “no!”. An interactive sitcom where you can only say “no” (or nothing at all). Negative Nancy is a choose your “no” adventure for people who have had enough.
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